Volume 95 Issue 26 | p. 9 | ConcentratesIssue Date: June 26, 2017Continuous crystallization of carbamazepineChemists build proof-of-concept system to evaluate control strategies and risks Science & Technology Concentrates As continuous manufacturing makes inroads in drug production, the process of continuous crystallization—in which active pharmaceutical ingredients are purified via solidification from a liquid phase—has proven to be a major roadblock. Looking to understand the risks...
Although scientists can use a few different methods to make a DNA-encoded library, the one they use most often treats the DNA like a bar code. They start by attaching a short piece of DNA to a small organic functional group—an aliphatic amine, for example. That basic building block is then split into wells in a plate, where it undergoes a chemical reaction with a different building block in each well.
The bonding-partner switcheroo that happens in metathesis reactions has been a boon for molecule makers. Chemists who made crucial discoveries in olefin metathesis even won the Nobel Prize in Chemistry back in 2005. But metathesis reactions in which the bonding partners on heteroatoms undergo a swap are rare.
Muck Rack makes it simple to find people, tweets, or articles that mention any name, keyword, company, hashtag etc. We've compiled this guide to help you make the most of your search.
Selecting a term
Start searching tweets, articles from media outlets, articles mentioned in tweets, journalists'
names, titles and bios with some suggested searches:
Companies or Topics (e.g. iPhone, Microsoft)
Phrases (e.g. "cloud computing") — use quotes to keep the terms together
Twitter handles (e.g. @username) — returns those who have mentioned or replied to
Names (e.g. "David Pogue")
Hashtags (e.g. #sxsw, #london2012)
Bio details (e.g. vegan, Olympics, father)
Muck Rack's Advanced Search allows for many boolean operators.
Find results that mention multiple specified terms, use AND or
+. For example, ensure each result contains both Elon Musk and Mark Zuckerberg by
searching Obama AND Romney or Obama + Romney.
Use the operators OR or , to broaden your search when you'd like either of
multiple terms to appear in results. (This is the default behavior of our search when no operators
are used.) For example, search for democrat OR republican to find results that refer to
Democrats and/or Republicans.
Use NOT or - to subtract results from your search. For
example, searching Disney will yield results about the Walt Disney Company as well as Walt Disney
World Resort. To exclude mentions of Disney World, search for Disney -World or Disney
When using one of these operators with a phrase, enclose it in quotation marks. For example, you can
find results about smartphones excluding Apple's iPhone 4S by searching smartphone -"iPhone
Exact case matching or punctuation
If you're searching for a brand name or keyword that relies on specific punctuation marks or capitalization, you can
find results that match your exact query by adding matchcase: before the keyword you're searching for, like matchcase:E*TRADE .
Use parentheses to separate multiple
boolean phrases. For example, to find journalists talking about having fun in Disney World or
Disneyland, search for ("disney world" OR disneyland) AND fun.
An asterisk can be used to search for any variation of a root word truncated by the asterisk. For example, searching for admin* will return results for administrator, administration, administer, administered, etc.
A near operator is an AND operator where you can control the distance between the words. You can vary the distance the near operation uses by adding a forward slash and number (between 0-99) such as strawberries NEAR/10 "whipped cream", which means the strawberries must exist within 10 words of "whipped cream".