Félicien Le Louedec on Muck Rack

Félicien Le Louedec

As seen in: Wiley Online Library, British Pharmacological Society, MDPI
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Articles

Exposure‐Response Analysis for Time‐to‐Event Data in the Presence of Adaptive Dosing: Efficient Approaches and Pitfalls

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By Alexandra Lavalley-Morelle, Félicien Le Louedec, France Mentré, Richard Anziano
| Wiley Online Library
What is the current knowledge on the topic? ○ In exposure-response analysis, the use of time-static metrics relying on patients' follow-up is not recommended as it may lead to false conclusions. Current findings promote the use of time-static metrics based on initial exposure. What question did this study address?
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Antibiotics | Free Full-Text | Loading Dose of Ceftazidime Needs to Be Increased in Critically Ill Patients: A Retrospective Study to Evaluate Recommended Loading Dose with Pharmacokinetic Modelling

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By Manon Launay, Edouard Ollier, Félicien Le Louedec, Benjamin Kably
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Investigating the clinical impact of dose‐banding for weekly paclitaxel in patients with breast cancer: A retrospective and monocentric study

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By Florent Puisset, Florence Dalenc, Félicien Le Louedec, Lorène Verguet
| British Pharmacological Society
ORIGINAL ARTICLE Funding information: No funding was received for this study. The authors confirm that the Principal Investigator for this paper is Prof Florence Dalenc, she had direct clinical responsibility for patients. Abstract Aims Dose-banding (DB) consists in approximating the theoretical dose of anticancer drugs calculated according to the body surface area (Dose-BSA) of patients. This concept is supported by pharmacokinetic but not by clinical data.
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