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Articles by Harmful Components

GPCRs as key regulators in wound healing

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By Harmful Components
| Frontiers
REVIEW article Front. Cell Dev. Biol. Sec. Signaling GPCRs as key regulators in wound healing 1. Center for High Altitude Medicine, Institute of High-Altitude Medicine, High Altitude Medicine Key Laboratory of Sichuan Province, Department of Dermatology & Venerology, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China 2. Department of dermatology and venereology, West China Hospital, Sichuan University, Sichuan University, Chengdu, China 3.
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Multiple analyses of main flavor components in reconstituted tobacco and transfer behavior of their key substances during heating

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By Jianyang Shi, Harmful Components, Yunxia Yang, Engineering Chengdu
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description jssc8308-sup-0001-SuppMat.xlsx138.6 KB Supporting Information REFERENCES 1, , , . Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer. J Proteome Res. 2014; 13: 982–996. 2, . Smoking and cardiovascular disease. Arterioscler Thromb Vasc Biol. 2014; 34: 509–515. 3, .
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Cysteine Catalyzed Pictet-Spengler Reaction: a Convenient and Mild Method for Synthesis of Spiroindolones - Catalysis Letters

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By Harmful Components
| link.springer.com
Abstract Pictet-Spengler reaction is one of the main ways to synthesize spiroindolones, which widely exists in natural products and pharmaceutical agents. We accidentally discovered bovine serum albumin (BSA) had catalytic activity for Pictet-Spengler reaction previously. After a series of exploratory experiments around the catalytic process, it was found that some amino acids played a key role. It is worth noting that, Pictet-Spengler reaction catalyzed by amino acids has been rarely described.
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