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Jungeui Hong

As seen in: BioRxiv, Cell Press, medRxiv
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Articles

Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms

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By Siyu Sun, Eunae You, Jungeui Hong, David Santiago Hoyos, Kaloyan M. Tsanov, Om Mattagajasingh, Andrea Di Gioacchino, Sajid A. Marhon, Jonathan A. Chacon-Barahona, Hua Jiang, Samira Hozeifi, Omar Rosas-Bringas, Katherine Xu, Yuhui Song, Evan Lang, Alexandra Rojas, Linda T. Nieman, Rajmohan Murali, Nicolas Vabret, Daniel Zenklusen, John Lacava, Scott Lowe, David Ting, Christine A. Iacobuzio-Donahue, Alexander Solovyov, Benjamin D. Greenbaum, Bidish K. Patel, Pharto Chanda, Ali Karacay
| Cell Press Verified
Results We integrated multiomics data, including whole-genome sequencing (WGS) and transcriptome sequencing collected from an autopsy PDAC cohort (Table S1) using a rapid multiregional sampling approach24 (Figure 1A). We first focused on L1 for samples with matched WGS and total RNA sequencing (RNA-seq) (Figure 1B, right).
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Convergence for Inactivation of TGFβ Signaling Is a Common Feature of Advanced Pancreatic Cancer

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By Jungeui Hong, Haochen Zhang, Elias-Ramzey Karnoub, Zachary Kohutek
| medRxiv
The authors have declared no competing interest. This work was funded by the NIH/NCI grant R35 (CA220508-03) and U2C (CA233284-03) awarded to C.A.I-D. Cycle for Survival for David Rubenstein Center for Pancreatic Cancer Research. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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Cancer cells co-evolve with retrotransposons to mitigate viral mimicry

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By Siyu Sun, Jungeui Hong, Eunae You, Kaloyan M. Tsanov
| BioRxiv
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