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Marcus D’Souza

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Articles

Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis

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By Sofia Sandgren, Sabine Schaedelin, Kiarra Ning, Aleksandra Maceski, Johanna Oechtering, Christian Cordano, Lester Melie-Garcia, Jeffrey M. Gelfand, Alessandro Cagol, Roland Henry, Sebastian Finkener, Patrice H. Lalive, Stefanie Muller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G Hemkens, Özgür Yaldizli, Bettina Fischer-Barnicol, Tobias Derfuss, Patrick Roth, Marina Herwerth, Claudio Gobbi, David Brassat, Björn Tackenberg, Rosetta Pedotti, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Georgina Arrambide, Fredrik Piehl, Henrik Zetterberg, Bruce A.C. Cree, Maria Pia Sormani, Ludwig Kappos, Stephen L. Hauser, Michael Khalil, Cristina Granziera, Ari J Green, David Leppert, Pascal Benkert, Ahmed Abdelhak, Jens Kuhle, Lisa M. Hofer, Michelle Hughes, Nafiye Genc, Riccardo Galbusera, Edoardo Galli, Jannis Müller, Veronika Kana, Catarina Raposo, Jorge R. Oksenberg, David Conen, Maximilian Einsiedler, Amar Zadic, Marjolaine Uginet
| JAMA Network Verified
Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis Key Points Question Are serum glial fibrillary acidic protein (GFAP) levels and their treatment-related changes associated with future progression independent of relapse activity (PIRA) in multiple sclerosis (MS)?
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Standardization and digitization of clinical data in multiple sclerosis

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By Marcus D’Souza, Athina Papadopoulou, Ludwig Kappos, Christophe Girardey
| Nature Verified
Abstract Standardization is necessary to ensure the reliability of clinical data and to enable longitudinal and cross-sectional comparisons of data obtained in different centres and countries. In patients with multiple sclerosis (MS), standardized clinical data are needed for monitoring of disability and for collecting real-world evidence for use in research.
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Electronic Neurostatus-EDSS increases the quality of expanded disability status scale assessments: Experience from two phase 3 clinical trials

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By Marcus D’Souza, Johannes Lorscheider, Antti Heikkilä, Vanessa Haller
| SAGE Publishing
Article Information Article first published online: May 7, 2019 Received: December 28, 2018; Revisions received: March 18, 2019; Accepted: March 30, 2019 Marcus D’Souza Neurology, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, Basel, Switzerland/NeuroCure Clinical Research Center, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin Humboldt-Universität zu Berlin and Berlin Institute of Health,...
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