This Rockford restaurant chain usually goes for it with the drink specials, but when it comes to the highest calorie meal in town, they aim to take that title too. Thrillist put together a story on the highest calorie chain restaurant meals and the results are staggering. The highest calorie meal on the list came from Cheesecake Factory . An order of chicken and biscuits comes in at 2,260 calories, 68g of fat and 2,870mg of sodium. That's a day of eating in only one sitting for most people.