An estimated prevalence rate for chronic, non-healing wounds in the United States is 2 percent of the general population. The staggering cost of managing these patients’ wounds exceeds $50 billion per year. This is 10 times more than the annual budget of the World Health Organization. The prevalence of chronic wounds is thought to be comparable to heart failure. However, unlike heart failure, little is known about the value of the treatments administered, or the outcome of these patients.