Ellen Pompeo, who plays the iconic Meredith Grey in Grey’s Anatomy may be the highest paid actress in TV, but it was no easy feat. Actually, she fought tooth and nail to be paid the same as Patrick Dempsey (who played Derek Shepherd. ) If you’re curious about how much she makes, it’s $20 million a year, or roughly $557k an episode. Dang. Are they holding auditions for a new red headed medical intern or resident? Break me off a piece of that Kit Kat bar.