Stuff You Should Know, often abbreviated as SYSK, is a free, award-winning podcast and video series published by the HowStuffWorks website and hosted by Josh Clark and Charles W. "Chuck" Bryant, both writers at HowStuffWorks. The podcast is consistently ranked in the Top 10 on iTunes. It is one of the most popular podcasts in the world, being downloaded millions of times each month.
The podcast, released every Tuesday and Thursday, educates listeners on a wide variety of topics, often using popular culture as a reference giving the podcast comedic value. The podcast is available for free on the iTunes Store and is one of the top downloaded podcasts. On January 19, 2013, a full-length SYSK TV show aired on Science Channel and ran for one season. Source