Escalier Biosciences, with offices in Encinitas and the Netherlands, said Tuesday that it has raised $19 million in venture capital financing. Privately held Escalier is developing drugs for psoriasis and other autoimmune disorders. The round was led by Forbion, a European life science venture fund. It included existing investors New Science Ventures and BioGeneration Ventures. Escalier’s drug candidates are in late-stage preclinical studies.
The revolutionary CRISPR/Cas9 gene editing system made it possible to rapidly and precisely alter DNA, the essential molecule of life. But DNA doesn’t work by itself, it relies on the messenger molecule RNA to carry out its instructions. Salk Institute scientists reported Thursday that they’ve invented a new version of the technology that works on RNA, combining CRISPR/Cas9’s precision with the ability to turn its effects on and off at will. And because it leaves DNA untouched, it’s safer.
Put down the scalpel and bring out the tape. That’s the prescription from La Jolla’s DermTech, which offers skin tests for melanoma using a special adhesive tape. The genomic tests can quickly identify those who need further attention and reassure those who test negative for the cancer. One test, called DermTech PLA (Pigment Lesion Assay), launched in 2016. It identifies lesions at high risk for melanoma through analyzing RNA. A second tape-based test, called Nevome, launched last month.
Muck Rack makes it simple to find people, tweets, or articles that mention any name, keyword, company, hashtag etc. We've compiled this guide to help you make the most of your search.
Selecting a term
Start searching tweets, articles from media outlets, articles mentioned in tweets, journalists'
names, titles and bios with some suggested searches:
Companies or Topics (e.g. iPhone, Microsoft)
Phrases (e.g. "cloud computing") — use quotes to keep the terms together
Twitter handles (e.g. @username) — returns those who have mentioned or replied to
Names (e.g. "David Pogue")
Hashtags (e.g. #sxsw, #london2012)
Bio details (e.g. vegan, Olympics, father)
Muck Rack's Advanced Search allows for many boolean operators.
Find results that mention multiple specified terms, use AND or
+. For example, ensure each result contains both Elon Musk and Mark Zuckerberg by
searching Musk AND Zuckerberg or Musk + Zuckerberg.
Use the operators OR or , to broaden your search when you'd like either of
multiple terms to appear in results. (This is the default behavior of our search when no operators
are used). For example, results will contain either cake or cookie by searching cake OR cookie or cake,cookie
Use NOT or - to subtract results from your search. For
example, searching Disney will yield results about the Walt Disney Company as well as Walt Disney
World Resort. To exclude mentions of Disney World, search for Disney -World or Disney
When using one of these operators with a phrase, enclose it in quotation marks. For example, you can
find results about smartphones excluding Apple's iPhone 4S by searching smartphone -"iPhone
Exact case matching or punctuation
If you're searching for a brand name or keyword that relies on specific punctuation marks or capitalization, you can
find results that match your exact query by adding matchcase: before the keyword you're searching for, like matchcase:E*TRADE .
Use parentheses to separate multiple
boolean phrases. For example, to find journalists talking about having fun in Disney World or
Disneyland, search for ("disney world" OR disneyland) AND fun.
An asterisk can be used to search for any variation of a root word truncated by the asterisk. For example, searching for admin* will return results for administrator, administration, administer, administered, etc.
A near operator is an AND operator where you can control the distance between the words. You can vary the distance the near operation uses by adding a forward slash and number (between 0-99) such as strawberries NEAR/10 "whipped cream", which means the strawberries must exist within 10 words of "whipped cream".