BSA bovine serum albumin CSR class switch recombination GC germinal center MBC memory B cell NP 4-hydroxy-3-nitrophenyl OVA ovalbumin PC plasma cell RBL rat basophil leukemia-2H3 RT room temperature WT wildtype 1 Introduction Food allergy is an immunological disorder associated with a significant health, quality of life, and financial burden [1, 2]. The production and persistence of allergen-specific IgE determines allergic reactivity to foods.