3D‐hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells‐Mediated Immunosuppression and Suppressing Oxidative Stress‐Induced Melanocyte Damage

1 Introduction Vitiligo is a common skin disease characterized by melanocytes destruction in the epidermis or mucous membrane and the resultant formation of white spots and patches, leading to patients’ disfiguration and anxiety that has brought a heavy burden to society and family[1] To date, numerous mechanisms have been identified to contribute to vitiligo pathogenesis, among which autoimmunity and oxidative stress are two cardinal events mediating melanocyte destruction.[2] Based on...