1 Introduction Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently recognized and independent disease entity. MOGAD is typically associated with acute disseminated encephalomyelitis, optic neuritis, or transverse myelitis. The presence of high titers (≥ 1:100) of MOG immunoglobulin G in serum (MOG-IgG) is unique to MOGAD [1, 2].