BioMedWorks’ Newsletter

Past BioMedWorks newsletters examined those specialized macrophage cells situated in the brain: microglia. Their roles are surprising: Sleep, anesthesia and norepinephrine: let’s revisit Microglial role in NE action.

I just finished the novel, “Salt of the Earth” narrating the story of the 1920’s ground breaking ‘clinical trial’ using iodized salt to treat endogenous goiter and cretinism in the Swiss Alps. It featured a village at the base of the Matterhorn, and moutaineering using their famous “alpenstocks”. I have long used trekking poles in my daily walks. Firm belief in its benefits.

Past newsletters discussed the intranasal route of administration, and how drug substance is transported directly to the base of the brain. Many therapeutics are dosed nasally, e.g. Narcan for opioid overdose reversal. Knowing the physiologic factors that impact delivery is crucial for development in this area. There are substantial impacts on nasal patency measurements depending upon the menstrual phase.

My past newsletters are oldies but goodies and deserve a relook and peruse. Today the sun has stood still… staying for the longest day time of the year. In Celtic societies, the summer solstice is known as Litha. People gather at Stonehenge for day and night long celebrations watching the sun align and shine through a certain point in the structure. This day is a happy celebration of the sun.

Past newsletters discussed the philosophy of mind, consciousness and collective unconscious described by Carl Jung. Incidents of synchronicity and cooperativity between and among multiple others, are indicative of this collective connection. To learn more, do use the search function at biomedworks.substack.com to see reports that go back for five years, so far.

Many past newsletters look at muscle and joint injury, and the innovations developing to improve outcomes. Just search on key words to find these. However, many orthopedists trained in the recent past immediately go to surgical solutions to ‘correct’ whatever is perceived to be the problem. Now researchers are taking an objective view to make comparisons of treatment options - both surgical and non.

Time again to feature the heart, its vasculature and impacting metabolic dysfunction. Topics include: stopping blood loss instruments engineered to help diabetics soy protein helping heart failure Remember, you can peruse past newsletters related to these topics - just search on keywords of interest. BioMedWorks’ Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

More info on cleaning up and clearing up Time again to learn new ways to renew and repair our bodies. Here is the latest research. Noisy static for clearer vision Age-related macular degeneration (AMD) is the leading cause of irreversible blindness among the elderly. Now researchers found an effective non-invasive way to improve the vision of people with AMD using augmented reality headsets that add a layer of “visual noise” over what they see.

Neuroscience is one of my favorite research topics. Several past letters report on progress in multiple areas. Use key words to peruse those topics. Today we look at: New pain path potential target Dementia/memory related findings: passion fruit, infections, and naps BioMedWorks’ Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Continue reading this post for free, courtesy of BioMedWorks.

My past newsletter described the amazingly important gland: the thymus. Now clinical researchers find that those who keep an intact thymus gland, have less cancer, autoimmunity and all cause mortality. Its existence correlates with a longer life. Researchers used artificial intelligence to analyze routine medical scans, uncovering how the thymus impacts aging, cardiovascular risk, cancer incidence, and response to immunotherapy.