Clinical Gastroenterology and Hepatology

Description The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update is to review the available evidence and expert advice regarding the clinical management of patients with suspected extraesophageal gastroesophageal reflux disease.

Article info Publication history Accepted: March 31, 2023 Received in revised form: March 14, 2023 Received: January 22, 2023 Publication stage In Press Journal Pre-Proof Footnotes Kristin Jorgensen: Writing – review & editing, Methodology, Data curation. Silje Syversen: Writing – review & editing, Methodology, Data curation. BRIGID BOLAND: Writing – review & editing. Lily Zou: Writing – review & editing, Methodology, Formal analysis.

Article info Publication history Accepted: March 29, 2023 Received in revised form: March 19, 2023 Received: December 10, 2022 Publication stage In Press Journal Pre-Proof Footnotes Bas Groot Koerkamp: Writing – review & editing, Investigation. Marco J. Bruno: Writing – review & editing, Supervision, Resources, Project administration, Methodology, Investigation, Funding acquisition, Conceptualization. Casper H. van Eijck: Writing – review & editing, Investigation. Djuna L.

Article info Publication history Accepted: March 21, 2023 Received in revised form: March 6, 2023 Received: November 4, 2022 Publication stage In Press Journal Pre-Proof Footnotes Grant Support This work was supported by the Medical Research Council & University of Edinburgh Precision Medicine PhD studentship (MR/N013166/1, to NC-C) and the UKRI Future Leaders Fellowship (MR/S034919/1, to CWL). CAV was funded by a Chancellor’s Fellowship provided by the University of Edinburgh.

Article info Publication history Accepted: March 1, 2023 Received in revised form: February 19, 2023 Received: November 14, 2022 Publication stage In Press Journal Pre-Proof Footnotes AUTHOR CONTRIBUTIONS: Study concept and design SF, DC, N Krugliak Cleveland, DTR Acquisition of data SF, DC, NK Choi, NMG, EAP Analysis and interpretation of data SF, NAC, DTR Drafting of manuscript NAC, TC, DTR Critical revision of manuscript SF, DC, NK Choi, NMG, EAP, NAC, RDC, SRD, JP, AS, N Krugliak...

Article info Publication history Accepted: February 21, 2023 Received in revised form: February 14, 2023 Received: December 13, 2022 Publication stage In Press Journal Pre-Proof Footnotes Matteo Tacelli: Investigation, Data curation. Antonio Facciorusso: Writing – original draft, Methodology, Formal analysis. Roberto Salvia: Investigation. Sundeep Lakhtakia: Investigation, Data curation. Luca Landoni: Writing – review & editing, Investigation, Data curation.

Article info Publication history Accepted: February 21, 2023 Received in revised form: February 15, 2023 Received: July 29, 2022 Publication stage In Press Journal Pre-Proof Footnotes Conflicts of Interest: AJS: None for this project. Dr. Sanyal is President of Sanyal Biotechnology and has stock options in Genfit, Akarna, Tiziana, Indalo, Durect Inversago and Galmed.

Description Alpha-gal syndrome is an emerging allergy first described in the early 2000s. The allergy can cause anaphylaxis, gastrointestinal (GI) symptoms, and skin changes one to several hours after ingestion of mammalian products. A GI phenotype that is increasingly recognized manifests with nonspecific symptoms like abdominal pain, diarrhea, nausea or vomiting without predominant skin, respiratory or circulatory symptoms.

Acute kidney injury (AKI) is a common complication among decompensated patients with cirrhosis and is associated with significant mortality. 1 Garcia-Tsao G. Parikh C.R. Viola A. Acute kidney injury in cirrhosis. In this setting, the most common phenotypes of AKI are hypovolemic/prerenal, acute tubular injury/necrosis, and hepatorenal syndrome (HRS). In this article, the most recent terminology put forth by the International Club of Ascites is used, HRS-AKI, which replaces the prior term HRS type 1.

Article info Publication history Accepted: January 13, 2023 Received in revised form: January 8, 2023 Received: August 15, 2022 Publication stage In Press Journal Pre-Proof Footnotes Guarantor of the article: ART Specific author contributions: - AF, CJK, and ART were involved in designing the study protocol and data collection tool - AF and AC were involved in data collection - RL and JM were involved with generation of matched cohort - RL and AF were responsible for data analysis - AF was...