Cellular and Molecular Gastroenterology and Hepatology
VerifiedJournal
CMGH is the newest peer-reviewed journal published by the American Gastroenterological Association (AGA), joining Gastroenterology and Clinical Gastroenterology and Hepatology (CGH). The mission of CMGH is to publish impactful digestive biology research that ranges from mechanisms of normal function to pathobiology and covers a broad spectrum of themes in gastroenterology, hepatology, and pancreatology. The journal reports the latest advances in cell biology, immunology, physiology, microbiology, genetics, and neurobiology of gastrointestinal, hepatobiliary, and pancreatic health and disease. The research CMGH publishes is hypothesis driven, mechanistically novel, and appropriately designed and powered. Studies published in CMGH address important questions and use in vitro models, tissues or cells from patients, and animal models to make fundamental discoveries and translate them to human disease. Source
Actions
Media Outlet details
| Scope | International |
|---|---|
| Language | English |
| Country | United States of America |
Similarweb UVM
|
Request pricing |
Comscore UVM
|
Request pricing |
| Accepts contributed content | Yes |
Recent Articles
Search ArticlesThe Endocannabinoid System Drives Eosinophil Infiltration During Eosinophilic Esophagitis
Keywords Eosinophilic Esophagitis Endocannabinoid System Monoacylglycerol (Monoglyceride) Lipase 2-Arachidonoylglycerol Esophageal Epithelial Cells Cannabinoid Receptors Abbreviations used in this paper 2-AG (2-arachidonoylglycerol) CB (cannabinoid) ECS (endocannabinoid system) EoE (eosinophilic esophagitis) IL (interleukin) ILC2 (group 2 innate lymphoid cell) ISH (in situ hybridization) KO (knockout) MGH (monoglyceride hydrolase) MGL (monoacylglycerol lipase) RT (room temperature) WT...
Cellular and Molecular Gastroenterology and Hepatology
These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.
Cellular and Molecular Gastroenterology and Hepatology
Please select at least one article in order to proceed.
Cellular and Molecular Gastroenterology and Hepatology
Please select at least one article in order to proceed.
Unleashing the Potential of Oral Deliverable Nanomedicine in the Treatment of Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), marked by chronic gastrointestinal tract inflammation, poses a significant global medical challenge. Current treatments for IBD, including corticosteroids, immunomodulators, and biologics, often require frequent systemic administration through parenteral delivery, leading to nonspecific drug distribution, suboptimal therapeutic outcomes, and adverse effects.
Endothelial Slc35a1 Deficiency Causes Loss of LSEC Identity and Exacerbates Neonatal Lipid Deposition in the Liver in Mice
The functional maturation of the liver largely occurs after birth. In the early stages of life, the liver of a newborn encounters enormous high-fat metabolic stress caused by the consumption of breast milk. It is unclear how the maturing liver adapts to high lipid metabolism. Liver sinusoidal endothelial cells (LSECs) play a fundamental role in establishing liver vasculature and are decorated with many glycoproteins on their surface.
Cellular and Molecular Gastroenterology and Hepatology
Please select at least one article in order to proceed.
Epithelial-Fibroblast Crosstalk in Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is an emerging form of food allergy that exerts a significant clinical and financial burden worldwide. EoE is clinically characterized by eosinophil-rich inflammatory infiltrates in esophageal mucosa and esophageal dysfunction. Remodeling events in esophageal epithelium and lamina propria also frequently occur in patients with EoE.
Rethinking the Roles of Cancer-Associated Fibroblasts in Pancreatic Cancer
Bearing a dismal 5-year survival rate, pancreatic ductal adenocarcinoma (PDAC) is a challenging disease that features a unique fibroinflammatory tumor microenvironment. As major components of the PDAC tumor microenvironment, cancer-associated fibroblasts are still poorly understood and their contribution to the several hallmarks of PDAC, such as resistance to therapies, immunosuppression, and high incidence of metastasis, is likely underestimated.
A Structure-function Analysis of Hepatocyte Arginase 2 Reveals Mitochondrial Ureahydrolysis as a Determinant of Glucose Oxidation
Restoring hepatic and peripheral insulin sensitivity is critical to prevent or reverse metabolic syndrome and type 2 diabetes. Glucose homeostasis comprises in part the complex regulation of hepatic glucose production and insulin-mediated glucose uptake and oxidation in peripheral tissues. We previously identified hepatocyte arginase 2 (Arg2) as an inducible ureahydrolase that improves glucose homeostasis and enhances glucose oxidation in multiple obese, insulin-resistant models.