Charles River Labs

Medical research technologies are advancing through artificial intelligence (AI), but why has the same impact not yet been seen for a tried-and-true technology like flow cytometry? While an era of AI-native biology in healthcare and drug development becomes a reality, the quality and precision of AI-outcomes are incumbent upon the scientists and clinicians who lead the charge. Flow cytometry is a cornerstone technique for high-throughput, single-cell analysis.

With allergy season tending to start earlier and last longer each year due to global warming, some regions are already feeling the effects.

The company Anacor Pharmaceuticals is making strides with its drug acoziborole, which is purported to cure the terrible disease sleeping sickness with a single dose of three pills. The drug was invented in 2009, but recently won approval from the European Medicines Agency (EMA) after trials in Africa. The drug is an antiprotozoal compound, and the parasite Trypanasoma is one of its targets.

How open-source software is transforming scientific research I did a fair bit of coding in the early part of my career in computer-aided drug design, and I can remember two instances where my limited mathematical ability brought me to a halt. I simply couldn’t understand what was written in a book or journal article and thus convert it into computer code. Even consulting colleagues only gave partial help. It was deeply frustrating as it hindered potentially interesting lines of research.

Glioma research, including for usually fatal glioblastoma, is evolving with innovative drugs and advanced technology, offering new hope against these aggressive brain cancers. Last year, the US Food and Drug Administration (FDA) for a devastating brain cancer that primarily strikes children.

What are the different types of vaccine platforms, and how are they used? Over the course of human history vaccines have transformed public health. The WHO estimates that 2-3 million lives are saved each year by current immunization programs, notably for children under 5 years old. Protection through vaccination is based on the ability of the immune system to remember the pathogens that are encountered.

Podcast Mar 17, 2026 | Mary Parker I am joined by Charles River's newest Senior Vice President, Chief Scientific & Innovation Officer Dr. Namandjé Bumpus to discuss her amazing career. From hands on research as Professor and Director of the Department of Pharmacology and Molecular Sciences at Johns Hopkins University School of Medicine, to Chief Scientist and later Principal Deputy Commissioner at the US Food and Drug Administration, Dr. Bumpus has seen every angle of the industry.

Researchers from the University of Texas at Dallas have published the results of a study on the tissue samples of 33 colorectal cancer patients. Using microindentation testing to measure the stiffness of both regular and cancerous tissue of the intestines and colon, researchers found that patients under 50 showed stiffer tissue than older patients. Biomechanical measurements like the observed stiffness could be indicators that tissue is prone to cancer.

Artificial intelligence (AI) tools deployed for flow cytometry are no longer experimental, but operational AI systems now perform automated quality control, detect acquisition instability, classify immune subsets, and in some cases predict clinical outcomes directly from high-dimensional data.

How the Charles River Viral Safety and Viral Clearance summit helped the biologics industry keep abreast of scientific, regulatory, and even public health challenges There is no doubt that large-molecule drugs produced by living organisms have transformed global drug development. Advances in molecular biology, such as recombinant DNA technology, and major scientific breakthroughs in immunology and oncology have led to rapid growth in biologic therapeutics.