Genetic Engineering & Biotechnology News

Home > Topics > Bioprocessing > Thar Process Partners with ExtrateX to Bring Prep to Process-Scale SFC to Europe Credit: Olga Yastremska/Getty Images Thar Process, based in Pittsburgh, PA, a specialist in supercritical CO2 extraction and purification technology (SFE and SFC), partnered with  ExtrateX, a French expert firm in supercritical fluid systems, to represent and distribute its advanced SFC systems throughout Europe.

Home > Topics > Infectious Diseases > How Bladder Cells Fight Hidden E. coli: New Insights Into Recurrent UTIs Credit: KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images Urinary tract infections (UTIs) are among the most common bacterial infections, frequently caused by Escherichia coli. But UTIs are known to be recurrent, even after antibiotic treatment.

Home > Topics > Cancer > Stroke Remodels Tumor Microenvironment to Promote Glioma Growth Credit: GDArts / iStock / Getty Images Plus The results of a study by researchers at Texas Children’s Duncan Neurological Research Institute (Duncan NRI), at Baylor College of Medicine and collaborating institutions have shown that stroke promotes glioma growth, and point to cellular and molecular mediators involved in the process, linking brain injury to malignant brain tumors.

Home > Topics > Genome Editing > New CRISPR-Based Tool Enables Genome-Wide Mutagenesis of Bacteriophages Credit: Marharyta Marko / iStock / Getty Images Plus Researchers at the University of Otago – Ōtākou Whakaihu Waka in New Zealand have developed a CRISPR-based method for systematically disrupting genes across bacteriophage genomes, creating a faster route to uncover gene functions and engineer phages for potential therapeutic and biotechnology applications.

Data from two studies using models of brain tissue and aged mice help explain how APOE4, a genetic risk factor for Alzheimer’s disease, damages the brain’s blood vessels and promotes the buildup of abnormal protein. The findings are published in two papers in the journals Cell and Cell Stem Cell.

Every step we take begins with a burst of calcium inside our muscle cells, causing them to contract. Using cryo-electron microscopy (cryo-EM), researchers at the Max Delbrück Center have revealed how muscle cell calcium channels, known as type-1 ryanodine receptors (RyR1), open synchronously.

Home > Topics > Bioprocessing > JNC Targets Bigger Molecules with Cellufine Credit: Image generated with Google Gemini The rapid expansion of viral vectors, vaccines, and other complex biologics is creating a familiar downstream-processing problem in a new form: the molecules and particles that manufacturers need to purify are getting bigger.

Home > Topics > Bioprocessing > Intense Media Pressure an Emerging Challenge in CHO Business Credit: Elkor/Getty Images Storing and preparing the culture media required to make protein therapeutics is a major challenge for biopharma, particularly given the growing interest in boosting output through intensification and continuous processing.

Home Topics Bioprocessing Altruist Biologics’ Suzhou Site Receives EMA GMP Certification Credit: SweetBunFactory / iStock / Getty Images Plus Altruist Biologics, a CDMO based in China, reports that its Suzhou commercial manufacturing facility has successfully passed a GMP inspection by the European Medicines Agency (EMA) with zero critical findings. This marks the first time the facility has successfully received EMA GMP certification.

Home > Topics > Cancer > Genialis and Inventia Life Science Collaborate to Link Patient Biology with 3D Pancreatic Cancer Models Pancreatic cancer, illustration. [Libre de droit/Getty Images] Genialis and Inventia Life Sciences agreed to work together to improve how new treatments for pancreatic cancer are tested and matched to the patients most likely to benefit.