HMP Global Learning Network

Artificial intelligence–assisted colonoscopy may mitigate the negative impact of inadequate bowel preparation on adenoma detection, according to a single-center retrospective study evaluating real-world performance of computer-aided detection (CADe). Investigators analyzed 3163 CADe-assisted colonoscopies and compared outcomes with 2516 non-AI procedures performed prior to implementation.

A low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (low-FODMAP) diet may improve diarrhea-predominant irritable bowel syndrome (IBS-D) by reducing mast cell activation and restoring intestinal barrier function, according to a translational study investigating the biologic mechanisms underlying dietary response.

Ghassan Abou-Alfa, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, New York, discusses results from the EMERALD-3 trial evaluating immunotherapy-based strategies combined with transarterial chemoembolization (TACE) in patients with unresectable hepatocellular carcinoma. The study assessed whether adding STRIDE alone or STRIDE plus lenvatinib to TACE could improve outcomes compared with embolization alone.

Results from the phase 3 EMERALD-3 trial demonstrated that combining STRIDE-based immunotherapy with transarterial chemoembolization (TACE), with or without lenvatinib, significantly improved progression-free survival (PFS) compared with TACE alone, supporting a potential new treatment strategy for patients with embolization-eligible hepatocellular carcinoma.

Hello, my name is Manal Abdelmalek. I am the director of the MASLD Clinical Research Program and a professor of medicine here at the Mayo Clinic in Rochester, Minnesota. And I have been asked to address how do I treat MASLD and MASH for any patient that would come into my clinic. I must say this is a very heterogeneous population of patients.

A new review of total ankle arthroplasty (TAA) techniques concludes that anterior and lateral TAA approaches can provide predictable outcomes and preserve motion for end-stage ankle arthritis.1 The review, published in the Journal of Bone and Joint Surgery Open Access, emphasizes the importance of appropriately matching surgical approaches to factors such as patient anatomy, deformity, soft-tissue considerations, implant requirements, and surgeon expertise.1 Authors note TAA has evolved from...

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Key Takeaways CMS CY 2027 OPPS/ASC Proposed Rule (US): Proposes 2.4% payment increases for services performed in OPPS and ASC settings, effective January 1, 2027 if finalized; 60-day comment period ends August 31, 2026. Skin substitutes (OPPS): Proposes continuing separate reimbursement for skin substitute application and products, maintaining $127.14 per sq. cm. for non-biological skin substitute products licensed outside PHS Act section 351; rate remains not geographically adjusted.

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