MDSpire

Frequent cannabis use may be associated with markers of increased epilepsy severity among patients with drug-resistant epilepsy. Investigators conducted a retrospective cohort study of adults with drug-resistant epilepsy admitted to a single academic tertiary epilepsy monitoring unit between 2019 and 2024. Drug-resistant epilepsy was defined as failure of adequate trials of 2 appropriately chosen and tolerated antiseizure medications.

When artificial intelligence (AI) is applied to medical images, it can be used to improve the diagnostic capability of physicians as well as to identify many features that humans are unable to see. From identifying biomarkers to guiding treatment decisions, AI in medical imaging has already demonstrated many use cases in research settings, yet few of these tools have yet to reach the clinic. In a session at the Cleveland Clinic A.I. Summit for Healthcare Professionals, Benjamin H.

Long workweeks meet erectile function Work stress may be coming home in more ways than one. In a 2026 study from Zhejiang University School of Medicine, researchers examined 826 full-time working men aged 22 to 40 years to see how the daily grind might follow them into the bedroom. Their workplace stress index captured working hours, promotion pressure, decision-making autonomy, supervisor support, and colleague relationships.

Federal authorities alleged that a Florida gastroenterologist unlawfully prescribed at least 127 controlled substance prescriptions and failed to maintain patient records. Twan Phanijphand, MD, a gastroenterologist in Fort Walton Beach, Florida, reached a $300,000 civil settlement with the federal government over allegations involving unlawful prescribing of opioids and other controlled substances under the Controlled Substances Act.

Omalizumab may be associated with a higher rate of treatment success compared with omalizumab-facilitated multiallergen oral immunotherapy among patients with multifood allergy in an intention-to-treat analysis of a randomized clinical trial. Investigators conducted stage 2 of the multicenter, double-blind, placebo-controlled OUTMATCH trial at 10 US academic centers.

Among moderate- to late-preterm newborns who required respiratory support shortly following birth, initiating support with 30% oxygen rather than room air did not reduce ongoing respiratory support when leaving the delivery room. Current international guidelines cite insufficient evidence to recommend an initial oxygen concentration for newborns at 32 to 35 weeks’ gestation.

OM-89 may strengthen antimicrobial defenses in bladder epithelial cells and limit the regrowth of uropathogenic Escherichia coli following antibiotic treatment by enhancing lysosomal function and intracellular antibiotic accumulation. Researchers investigated the direct effects of OM-89, an orally administered bacterial lysate used for recurrent UTIs, using mouse and human bladder organoids and differentiated epithelial monolayers.

Adjunctive azithromycin use may have increased substantially among patients undergoing unscheduled cesarean delivery in the United States following publication of trial evidence. Investigators conducted a retrospective difference-in-differences analysis using Epic Cosmos electronic health record data from 2013 to 2024.

High-dose oral vitamin D was associated with rapid symptomatic and objective improvement in chemotherapy- and radiation-associated toxic effects of the skin, with no treatment-related adverse events. Researchers conducted a retrospective multicenter case series of 33 patients treated by oncodermatologists at 3 academic medical centers between December 2021 and January 2024.

Misleading information in an artificial intelligence–generated summary may alter subsequent recall of an event. Investigators combined an analysis of artificial intelligence (AI)-generated video summaries with an online experiment involving US adults. For the summary analysis, ChatGPT-5.5 and Gemini 2.5 Flash-Lite each summarized 2 25-second animated videos depicting a car-pedestrian accident 5 times per video, yielding 20 summaries.