Memorial Sloan Kettering Cancer Center

Dr. Jonathan Rosenberg says the emergence of enfortumab vedotin as a therapy for muscle-invasive urothelial carcinoma “feels like a huge sea change in how we treat patients, and hopefully a turning point toward longer survival in this difficult disease.” This story was originally published in December 2025. It was updated on July 14, 2026. A powerful treatment for bladder cancer provides lasting survival benefits, new follow-up data from clinical trials confirms.

The lab of MSK cancer immunologist Dr. Andrea Schietinger and colleagues at Weill Cornell Medicine found that a small subset of T cells, called stem T cells, are responsible for making new T cells and for continuously replenishing them in chronic disease. The findings open the door to new treatment strategies for chronic conditions like cancer, autoimmune diseases, and infections. T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells.

The final paper from the lab of the late MSK Developmental Biology Chair Kathryn Anderson reveals how a critical signaling molecule called WNT guides cells in the embryo from a state of high flexibility — known as "plasticity" — toward distinct, specialized identities. Completing the study was a labor of love for her colleagues.

Skip to main content Skip to footer Thanks to treatment at MSK, Christina, shown here with her husband, Kevin, was able to walk down the aisle as a bridesmaid at her sister-in-law's wedding. For people living with advanced triple-negative breast cancer (TNBC), a newly approved treatment may offer more time and a better quality of life.

New research from Memorial Sloan Kettering Cancer Center (MSK) investigates how a natural antifungal compound produced by helpful gut bacteria might help protect vulnerable patients; finds that a protein “fingerprint” in blood could predict dangerous clots in cancer patients; uncovers Americans’ changing relationship with dietary supplements; and reveals how NK cells respond to infections so quickly.

Skip to main content Skip to footer Urologic surgeon Dr. Massimiliano Spaliviero says MSK has made many advances in prostate cancer treatment, including determining the true level of risk from the disease. This allows MSK experts to recommend the most appropriate care for each patient and whether the cancer can be closely monitored with active surveillance. The outlook for people with prostate cancer has greatly improved in recent years.

The MSK MorPhiC team, left to right: Drs. Lorenz Studer, Danwei Huangfu, Ting Zhou, and Thomas Vierbuchen. Imagine you inherit a house only to discover that there are no labels on any of the breakers in the circuit box. How would you go about figuring out which switch did what? One approach: Turn on all the lights and appliances, then flip each breaker off one at a time to see what changes.

New research from Memorial Sloan Kettering Cancer Center (MSK) decodes how mesothelioma evades immunotherapy; shows why a common kidney cancer treatment combination falls short; and supports a free, open-source AI-driven drug discovery initiative. Decoding how mesothelioma evades immunotherapy A team led by scientists from MSK has discovered why some pleural mesothelioma tumors stop responding to immunotherapy — and found potential ways to fix it.

New research by MSK's Dr. Christine Mayr and team revealed how the largely overlooked "tail" region of mRNAs helps ensure key regulatory proteins get folded correctly — a fundamentally new understanding of their role. Proteins are how cells get work done. They carry out nearly every important cellular task, from ferrying messages to controlling which genes are turned on or off.

Dr. Selwyn Vickers, MSK’s President and CEO Dear MSK Community, It’s remarkable that more people are surviving cancer today than at any point in human history. By 2040, we expect that there will be more than 26 million cancer survivors in the United States alone and that 7 in 10 people diagnosed with cancer will be alive five years later. These aren’t just statistics — they represent millions of individual triumphs, families kept whole, and futures reclaimed.