Review of Optometry

When interpreting normative RNFL thickness values in highly myopic eyes, researchers argue that both axial length and age should be taken into account. In their study of more than 23,000 eyes, they observed that RNFL thickness normally increases with axial length up to about 24mm, plateaus through 26.5mm and then declines in highly myopic adults. Photo: Alia Cappellani, OD. Click image to enlarge.

Pre-existing immune-mediated disorders such as thyroid disease, psoriasis, inflammatory bowel disease and rheumatoid arthritis can predict structural changes and higher disease recurrence in patients with CSCR, this study found. Photo: Mohammad Rafieetary, OD, Jessica Haynes, OD, and Roya Attar, OD. Click image to enlarge.

Epithelial HSK may appear more self-limiting and less harmful than other forms of HSK. However, recent evidence suggests the disease can affect other corneal layers, and the resulting damage may become permanent with recurrent episodes. Photo: Lisa Marten, MD. Click image to enlarge. In a recent study, researchers investigated the morphological changes of corneal endothelial cells in patients with paracentral epithelial herpes simplex keratitis (HSK).

Epithelial HSK may appear more self-limiting and less harmful than other forms of HSK. However, recent evidence suggests the disease can affect other corneal layers, and the resulting damage may become permanent with recurrent episodes. Photo: Lisa Marten, MD. Click image to enlarge. In a recent study, researchers investigated the morphological changes of corneal endothelial cells in patients with paracentral epithelial herpes simplex keratitis (HSK).

In eyes with NTG and high myopia, circumpapillary choroidal thickness sectoral abnormalities may provide complementary pathophysiologic data (e.g., highlighting eyes where vascular insufficiency may contribute) and could enrich risk stratification when combined with OCT-A perfusion metrics, systemic vascular measures and circumpapillary RNFL thickness. Photo: Sarah B. Klein, OD. Click image to enlarge.

Perinatal brain injury is associated with lower two-year strabismus treatment success and greater postoperative drift in children, which can help guide preoperative counseling and management, researchers suggest.Photo: Sgfin/Wikimedia Commons. Click image to enlarge. Infants who sustain perinatal brain injuries within the first year of life commonly go on to develop strabismus, but managing this condition can present clinical challenges.

SSRIs are commonly prescribed antidepressants due to their efficacy and favorable safety profiles, but recent studies suggest that long-term use may be linked to ocular side effects such as impaired night vision, decreased visual acuity, optic neuropathy, mydriasis, angle closure and morphologic changes in the retina.Photo: Getty Images. Click image to enlarge.

This study identified two distinct peripheral vascular phenotypes in retinitis pigmentosa: Type 1, or terminal remodeling, and Type 2, or simple atrophy. The former type was associated with greater disease severity and worse visual function. Photo: Rami Aboumourad, OD. Click image to enlarge.

A review of 41 studies highlighted an association between greater early choroidal thickening and reduced axial elongation at one year in patients being treated for myopia. Among the interventions studied, choroidal responses were most pronounced in patients receiving repeated low-level red-light therapy. Photo: Iovino C, et al. Clin Ophthalmol. August 13, 2026. Click image to enlarge.

Multivariable analysis of 190 patients with RAO confirmed that younger age and worse baseline visual acuity were the primary determinants of clinically meaningful visual improvement, underscoring that baseline severity and retinal viability outweigh most therapeutic interventions once ischemic damage has occurred. Photo: Diana Shechtman, OD. Click image to enlarge.