South African Pharmaceutical Journal

M Leuschner University of Pretoria N de Beer University of Pretoria N Schellack University of Pretoria Abstract For drugs with a narrow therapeutic index (NTI) like tacrolimus, small changes in dosage can lead to significant changes in blood levels, which can affect both the effectiveness of the drug and the risk of adverse effects. Monitoring is crucial to ensure that the drug is maintained within the desired therapeutic range.

The successful management of chronic diseases such as atopic dermatitis relies greatly on adherence to treatment. The likelihood of adherence requires much more than a simple transfer of knowledge: a change in individuals’ behaviour towards health is needed. One of the critical components of this change is therapeutic patient education.

Abstract After serving for three terms as President of PSSA it is time to hand over the baton to a new President, who with his new committee, will take the PSSA forward. I will still have the privilege to be part of the Presidential Committee, but in a much different capacity. Section President's Message By submitting manuscripts to SAPJ, authors of original articles are assigning copyright to Medpharm Publications (Pty) Ltd.

Keywords: hypertension, blood pressure, cardiac output, peripheral vascular resistance Abstract This article outlines the principles of blood pressure, including normal and dysfunctional physiology, mathematical equations of pressure, definitions of hypertension and diagnosis, and hence the rationale for and mechanisms of treating hypertension in order to reduce cardiovascular and cerebrovascular risk. Author Biographies J A Ker, University of Pretoria Emeritus Professor of Medicine,...

Abstract The healthcare space is dynamic and constantly changing. What one learnt five years ago in their Bachelor of Pharmacy or Pharmaceutical Sciences degree is probably outdated or has evolved. Some laws have been phased out, some have been introduced; some problems have been solved, some are still escalating and more are developing. Whilst this may make many feel uncomfortable, the truth is that things always need to be changing for growth to occur.

Abstract The SAACP held its 72nd AGM on Sunday, 13 August 2023. The President’s Annual Sectoral Report can be viewed via this link: https://drive.google.com/file/d/1UEaTYnw0xp5-MT2SrpbJX3jF4Y3CBjMk/view?usp=sharing. During the AGM, the SAACP elected new Office Bearers. Mr Johannes Ravele was re-elected as President, Mr Jameel Kariem was elected as Vice-President, Mr Frans Landman was elected as Honorary Treasurer, and Mr Taki Kyriacos was re-elected as the Honorary Secretary.

Abstract PSSA AGM; The PSSA/Alpha Pharm distance learning programme 2023; The PSSA/Alpha Pharm clinical education programme 2023 for pharmacy staff. Section PSSA Perspectives By submitting manuscripts to SAPJ, authors of original articles are assigning copyright to Medpharm Publications (Pty) Ltd. Authors may use their own work after publication without written permission, provided they acknowledge the original source.

Nhlanhla G Mafarafara SAAHIP Abstract What is the ideal picture of hospital pharmacy in South Africa within the National Health Insurance (NHI) paradigm? I am sure you all have your opinion. Some based on current challenges, some based on the recent Covid-19 pandemic and some based on science. Author Biography Nhlanhla G Mafarafara, SAAHIP By submitting manuscripts to SAPJ, authors of original articles are assigning copyright to Medpharm Publications (Pty) Ltd.

Allergic rhinitis (AR) is a common condition that affects children from a very young age. It is often misdiagnosed as viral rhinosinusitis and erroneously treated with first-line over-the-counter medication, which will not only be ineffective, but may also lead to medication side-effects. Untreated AR can lead to serious complications. Trigger identification can be done using skin-prick testing and serum IgE-measurement – but this should be performed early.

Allergic diseases affect many people across the globe. They significantly impact on the quality of life of the people who are affected, creating personal and economic predicaments. Some of the most commonly diagnosed allergic diseases include atopic dermatitis, rhinitis, allergic conjunctivitis and sinusitis.