ScienceDirect

Published by: Elsevier Published by Show more The evolving virulence and pathogenesis of Pteropine orthoreovirus: An update Author links open overlay panelRabab Fatima Show more Keywords Pteropine orthoreovirus (PRV) ; ; ; ; ; Section snippets CRediT authorship contribution statement Rabab Fatima: Writing – review & editing, Writing – original draft, Supervision, Conceptualization.

Vaccine Volume 80, 30 April 2026, 128535 Transient elevation of NT-proBNP after mRNA COVID-19 vaccination in healthy adults: A longitudinal biomarker analysis Author links open overlay panelPavel Dlouhý a, Marek Petráš b , Ivana Králová Lesná c d, Roman Máčalík e, Jan Polák f g, Antonín Jabor h, Vanda Filová h, Jan Piťha i, Oliver Kuchař j k, Jozef Rosina l m Show more Highlights • NT-proBNP peaked within 14 days after the second vaccine dose.

Preclinical safety and toxicokinetic evaluation of TJ0113, a first-in-class mitophagy inducer for Parkinson's disease Author links open overlay panelYanan Tian a b 1, Fengqi Wang a b 1, Jikai Shen a, Ruiqi Zhang e, Qianwen Chen e, Le Xu a, Dong Liu c, Mengyang Fan c, Zhen Tian c, Xufeng Cen a , Xiaoyan Xu a , Hongguang Xia a b d Show more Highlights • Most mitophagy inducers lack GLP-compliant preclinical toxicological evaluation.

Rethinking dynamic difficulty adjustment for video game design Author links open overlay panelZhixing Guo a, Ruck Thawonmas b, Xiangshi Ren a Show more Highlights • Current Dynamic Difficulty Adjustment (DDA) is limited by Flow theory. • We redefined DDA as a game difficulty control mechanism. • We argue DDA should be taken in player-game interaction. • DDA should be utilized for precise control of game difficulty processes. • DDA should be designed towards specific design goals.

Muscle in fat trouble: The rise of IMAT in metabolic and musculoskeletal disease Author links open overlay panelVanessa M. Weik 1, Andreas L. Birkenfeld 2 3 4, Andreas Peter 1 2 3, Cora Weigert 1 2 3, Simon I. Dreher 1 2 3 Show more Abstract Intermuscular adipose tissue (IMAT) is increasingly recognized as a contributor to insulin resistance and metabolic dysfunction in type 2 diabetes (T2D).

Highlights • YOLOv8 identified intraerythrocytic Plasmodium species on thin smears. • Morphological cellular mimics were differentiated from parasites. • External validation used independent endemic thin-smear slides. • Automated screening outperformed microscopists in sensitivity. • Real-world smear heterogeneity was incorporated into model evaluation. Abstract Microscopic examination of Giemsa stained thin blood films remains the reference standard for malaria diagnosis.

Published by: Elsevier Published by Show more Minor harbours as dispersal hubs in the Mediterranean Sea: The case of non–indigenous species in an Italian port Author links open overlay panelAntonina Badalucco a b, Fabio Bozzeda b c, Fabio Crocetta b d, Andrea Desiderato e, Cengiz Koçak f, Joachim Langeneck g, Emanuele Mancini b c, Caterina Martino a, Francesco Mastrototaro h i, Serena Mucciolo e, Luigi Musco j, Maria Giovanna Parisi a b, Antonietta Rosso i k, Yann Toso a b, Sabrina Lo Brutto...

Highlights • All-electric intelligent cleaning equipment is developed for heliostat in tower CSP plants. • Dual dry/water modes achieve 93.23% and 99.05% heliostat reflectance recovery. • Adaptive pulse spray delivers substantial water savings for CSP heliostat cleaning. • An intelligent system enables highly effective cleaning in desert-Gobi CSP plants. • It addresses key O&M challenges of dense solar fields in desert-Gobi areas.

Highligths • Developed sustainable micro-LLE using ethyl acetate as a green DCM substitute. • Method achieves MLOQs 0.05–10 µg/L, linearity R²>0.995, and RSD <15%. • Achieved high sensitivity for pesticide and plasticizer detection in real samples. Abstract The determination of trace-level semi-volatile organic compounds (SVOCs) following EPA Method 8270 traditionally relies on manual liquid-liquid extraction (LLE) using large volumes of dichloromethane (DCM).

Sociosexual orientation, life history strategy, and reproductive success: A large-scale cross-cultural analysis across 92 contemporary societies Author links open overlay panelDmitry Grigoryev a 1 ⁎ , Albina Gallyamova a 1 , Elizaveta Komyaginskaya a 1 , Oulmann Zerhouni b 2 , Fanny Lalot c 2 , Laith Al-Shawaf d n , Linda H. Lidborg e, Ezgi Toplu-Demirtaş f , Anastasiya A.