IEEE Transactions on Biomedical Engineering

Authors: Samy Mokhtari, Jean-Michel Badier, Christian G. Bénar, Bruno Torrésani The accurate reconstruction of extended cortical activity from M/EEG data is a difficult, ill-conditioned problem. Improving brain sources localization, and overcoming current limitations of classical distributed methods, is an important and ongoing effort for both mathematicians and practitioners, especially for clinical applications such as epilepsy.

Authors: Yueyue Xiao, Chunxiao Chen, Jing Xia, Yubin Zheng, Liang Wang, Ming Lu, Jagath C. Rajapakse Tumor Treating Fields (TTFields) therapy, a clinically established modality that disrupts cancer cell mitosis through biophysical mechanisms, presents a unique paradigm in oncology. Despite its proven efficacy, its broad application is hindered by significant challenges in optimizing treatment delivery for individual patients.

Authors: Eleonora Storto, Massimiliano Solazzi, Mario Meola, Antonio Frisoli, and Francesco Porcini Ultrasound is a safe, non-invasive, and widely used diagnostic technique, but access to expert examinations remains limited in remote, emergency, and resource-constrained settings. Robotic teleultrasound addresses this problem by enabling physicians to perform remote ultrasound examinations through teleoperated systems.

Authors: Begum Kasap, Mahya Saffarpour, Weitai Qian, Rishad Raiyan Joarder, Kourosh Vali, and Soheil Ghiasi Non-invasive monitoring of fetal oxygenation remains a critical challenge in obstetric care, as current technologies such as cardiotocography lack direct measurement of oxygen saturation and can lead to unnecessary interventions.

Authors: Jie Chen; Xinyue Han; Zhuoheng Liu; Chengqian Zhou; Rui Hu; Saira Tabassam; Season K. Wyatt-Johnson; Adrian L. Oblak; Randy R. Brutkiewicz; Mingquan Lin; Nian Wang Alzheimer’s disease (AD) is the most common progressive neurodegenerative disorder. One of the primary hallmarks of AD is beta-amyloid (Aβ) deposition, and its accumulation is closely tied to disease progression. However, accurate detection of individual Aβ plaques remains technically challenging.

Authors: Dema N. Govalla, Anish S. Niadu, Dhrubo Ahmad, Jerzy W Rozenblit This study presents a solution to limitations such as the lack of palpation feedback in robot-minimally invasive surgeries. The solution involves creating a tactile feedback system that uses a novel tactile sensor to capture two characteristics needed for organ or tissue palpation in RAMIS—precisely identifying an internal organs deformation and texture type during robotic surgery.

Authors: Eysteinn Finnsson, Eydís Arnardóttir, Kristófer Montazeri, Brendan T. Keenan, Richard J. Schwab, Thorarinn Gislason, Allan I. Pack, Andrew Wellman, Anna S. Islind, Jón S. Ágústsson, Scott A. Sands Obstructive sleep apnea is commonly assessed using airflow sensors in polysomnography, yet standard nasal-pressure measurements can be distorted when patients breathe partly or predominantly through the mouth.

Authors: Tolga Çukur, Salman UH. Dar, Valiyeh A. Nezhad, Yohan Jun, Tae Hyung Kim, Shohei Fujita, Berkin Bilgic MRI supports a wide range of diagnostic and research applications through diverse acquisition protocols that capture complementary aspects of tissue structure and function. However, these capabilities often come at the cost of prolonged scan times, limiting efficiency, increasing sensitivity to motion, and constraining clinical workflows.

Authors: Juhyeon Lee, Brandon Oubre, Jean-Francois Daneault, Christopher D. Stephen, Jeremy D. Schmahmann, Anoopum S. Gupta*, Sunghoon Ivan Lee* (*Co-corresponding authors) Wearable technologies offer a promising path toward frequent and objective assessment of ataxia severity. However, most existing approaches rely on hand-crafted inertial features that are directly optimized against clinician-evaluated rating scales.

Authors: Chunchu Zhu, Xunjie Chen, and Jingang Yi This study presents an assistive control framework for bilateral knee exoskeletons designed to support human walking on granular terrain (i.e., sands), aiming to enhance ambulation ability while reducing muscle activation and metabolic cost. The study first analyzed how walking on sand differs from walking on solid ground and demonstrated terrain-dependent changes in human knee kinematics, joint moments, and ground reaction forces (GRFs).