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The diagnosis of small bowel motility disorders relies on the detection of abnormal contractile patterns by intestinal manometry. Criteria for abnormality were established using conventional intestinal manometry systems with few pressure sensors at relatively long intervals. In this study, high-resolution intestinal manometry detected established criteria of dysmotility with equal sensitivity and specificity as conventional manometry.
Prebiotics have been shown to reduce abdominal symptoms in patients with functional gut disorders, despite that they are fermented by colonic bacteria and may induce gas-related symptoms. To investigate changes in the metabolic activity of gut microbiota induced by a recognised prebiotic. Healthy subjects (n = 20) were given a prebiotic (2.8 g/day HOST-G904, HOST Therabiomics, Jersey, Channel Islands) for 3 weeks.
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