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Diagnostics Clinical Diagnosis The most common presentation of patients with diverticulitis is pain in the left lower abdominal quadrant and changes in bowel habits (constipation or diarrhea) with or without fever.
Background: The standard of care for acute uncomplicated diverticulitis today is antibiotic treatment, although there are no controlled studies supporting this management. The aim was to investigate the need for antibiotic treatment in acute uncomplicated diverticulitis, with the endpoint of recovery without complications after 12 months of follow‐up.
Abstract en Background Two RCTs (AVOD and DIABOLO) demonstrated no difference in recovery or adverse outcomes when antibiotics for acute uncomplicated diverticulitis were omitted. Both trials showed non‐significantly higher rates of complicated diverticulitis and surgery in the non‐antibiotic groups. This meta‐analysis of individual‐patient data aimed to explore adverse outcomes and identify patients at risk who may benefit from antibiotic treatment.
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