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A. E. Justice

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Articles by A. E. Justice

Insights from the largest diverse ancestry sex-specific disease map for genetically predicted height - npj Genomic Medicine

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By A. Papadopoulou, M. Graff, Z. Wang, I. J. Kullo, N. S. Josyula, L. Yengo, A. R. Wood, I. A. Holm, F. D. Mentch, H. Hakonarson, K. Kiryluk, O. Dikilitas, M. G. Hayes, W. -Q. Wei, T. L. Assimes, A. E. Justice, Y. V. Sun, P. Deloukas
| Nature Verified
Abstract We performed ancestry and sex specific Phenome Wide Association Studies (PheWAS) to explore disease related outcomes associated with genetically predicted height. This is the largest PheWAS on genetically predicted height involving up to 840,000 individuals of diverse ancestry. We explored European, African, East Asian ancestries and Hispanic population groups. Increased genetically predicted height is associated with hyperpotassemia and autism in the male cross-ancestry analysis.
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