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A. Edel

As seen in: Canadian Journal of Cardiology
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Articles by A. Edel

OXIDIZED PHOSPHATIDYLCHOLINES (OXPC) INDUCE CELL DEATH IN CARDIOMYOCYTES THROUGH FERROPTOSIS

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By D. Nelson, A. Edel, A. Stamenkovic, K. O'Hara
| Canadian Journal of Cardiology Verified
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Reperfusion is a major therapeutic aim in the treatment of acute myocardial infarction. The process of ischemia followed by reperfusion (I/R) is followed by the activation of an intense burst of reactive oxygen species (ROS) that we have shown to generate oxidized phosphatidylcholines (OxPC).
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TARGETED LIPIDOMIC ANALYSIS OF KIDNEY DURING ISCHEMIA AND REPERFUSION INJURY: IDENTIFICATION OF BIOACTIVE LIPIDS

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By A. Ravandi, Z. Solati, A. Edel, Y. Shang
| Canadian Journal of Cardiology Verified
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Ischemia/reperfusion (I/R) leads to series of cellular responses such as release of reactive oxygen species, elevation of apoptotic molecules, necrosis, inflammation and release of bioactive compounds cause structural damage. Oxidized phosphatidylcholines (OxPCs) are the most abundant compounds produced during reperfusion due to oxidative stress.
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