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No abstract is available for this article. References 2025. “Artificial Intelligence and Palliative Care.” International Journal of Palliative Nursing 31, no. 8: 367–368. https://doi.org/10.12968/ijpn.2025.0056. , , , , and . 2023. “Telemedicine in Cancer Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Pain Medicine 24, no. 3: 226–233. https://doi.org/10.1093/pm/pnac128. , , , , and . 2025.
Studies of targeted therapy resistance in lung cancer have primarily focused on single gene alterations. Based on prior work implicating APOBEC mutagenesis in histological transformation of EGFR-mutant lung cancers, we hypothesized that mutational signature analysis may help elucidate acquired resistance to targeted therapies.
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