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Keywords genomic imprinting DNA methylation naive pluripotency epigenetic instability QTL mapping diversity outbred mice Introduction Naive pluripotent stem cells (nPSCs) are capable of extensive ex vivo self-renewal, amenable to lead genome engineering, and can differentiate into all somatic cell types. This combination of features makes nPSCs, in principle, tailor-made for regenerative medicine applications.
LETTER TO THE EDITOR S. Taka Corresponding Author E-mail address: staka@med.uoa.gr Allergy Dpt, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece Correspondence to Taka S 1. Allergy Dpt, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece. Tel: +30‐210 7776964 Email: staka@med.uoa.gr Search for more papers by this author S.
Nab-paclitaxel as second line treatment in advanced gastric cancer: A HORG multicenter phase II study P. Katsaounis, N. Kentepozidis, A. Kotsakis, A. Polyzos, L. Vamvakas, M. Bakogiorgos, I. Boukovinas, E. Hartabilas, E. Prinarakis, T. Skaltsi, V. Georgoulias and J.
Background: Triple negative breast cancer (TNBC) is a heterogeneous classification to which various subtypes are included. At present, TNBC lacks a standard targeted therapeutic strategy, other than conventional cytotoxic agents. The combination of weekly carboplatin and paclitaxel is active and well tolerated. In addition, bevacizumab when added to paclitaxel prolonged progression-free survival (PFS) in metastatic breast cancer (MBC).
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