Activated phosphoinositide 3-kinase delta syndrome (APDS) is a combined immunodeficiency that results from heterozygous gain-of-function mutations involving the genes encoding PIK3CD. Clinical manifestations include immune deficiency, autoimmunity and lymphoma. To read this article in full you will need to make a payment ACAAI Member Login ACAAI Member, full access to the journal is a member benefit. Use your society credentials to access all journal content and features.
