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In this multinational population-based study of adults, aged 40 years and above, we show that people with spirometric SAO are more likely to report dyspnoea, chronic cough, chronic phlegm, and wheeze. Additionally, they are more likely to have had a diagnosis of cardiovascular disease, but not hypertension or diabetes. A worse quality of life is also associated with spirometric SAO.
Previous studies have reached conflicting conclusions about the role of atopy as a risk factor for COPD. In part, this is attributable to variation in the definitions of airflow limitation and the treatment of people with asthma. To establish whether there is any independent association between atopy and post-bronchodilator airflow limitation in the general population aged 40 years and over.
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