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Articles by Aaron Dou
Methylation-based ctDNA monitoring in metastatic breast cancer during CDK4/6 inhibitor therapy
Abstract Circulating tumor DNA (ctDNA) enables minimally invasive treatment monitoring, yet the clinical validity of longitudinal ctDNA surveillance in metastatic breast cancer remains incompletely defined.
Longitudinal evaluation of serial ctDNA kinetics using joint modeling in patients with metastatic breast cancer
Abstract This study applies joint modeling (JM) of longitudinal and time-to-event data to circulating tumor DNA (ctDNA) dynamics measured by liquid biopsy in metastatic breast cancer (mBC), with a focus on dynamic prediction. Unlike traditional prognostic approaches that rely on static biomarkers, JM captures the continuous evolution of a methylation-based tumor fraction (TF) and links these changes to clinical outcomes.
Integration of Social Media to Enhance Engagement With a Medical Education Website: A Content Analysis
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
LRIG1 controls proliferation of adult neural stem cells by facilitating TGFβ and BMP signalling pathways - Communications Biology
Abstract Adult Neural Stem Cells (aNSCs) in the ventricular-subventricular zone (V-SVZ) are largely quiescent. Here, we characterize the mechanism underlying the functional role of a cell-signalling inhibitory protein, LRIG1, in the control of aNSCs proliferation.
Utilization and Impact of a Radiation Nursing Clinic to Address Acute Care Needs for Patients with Gynecologic Cancers
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