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Articles by Aaron S. Dumont
An unusual finding of the Porus trigeminus: Case report with histological findings
Abstract Many anatomical variants can potentially contribute to trigeminal neuralgia. These include compression by the superior cerebellar artery and less commonly, bony compression near the trigeminal cave. Herein, we report the gross and histological findings of a cadaveric specimen found to have a bony roof of the trigeminal cave. During the routine dissection of a male cadaver, an unusual finding of the skull base was observed.
Establishment and Application of a Novel In Vitro Model of Microglial Activation in Traumatic Brain Injury
Abstract Mechanical impact-induced primary injury after traumatic brain injury (TBI) leads to acute microglial pro-inflammatory activation and consequently mediates neurodegeneration, which is a major secondary brain injury mechanism. However, the detailed pathologic cascades have not been fully elucidated, partially because of the pathologic complexity in animal TBI models. Although there are several in vitro TBI models, none of them closely mimic post-TBI microglial activation.
Establishment and application of a novel in vitro model of microglial activation in traumatic brain injury
Abstract Mechanical impact-induced primary injury after traumatic brain injury (TBI) leads to acute microglial pro-inflammatory activation and consequently mediates neurodegeneration, which is a major secondary brain injury mechanism. However, the detailed pathological cascades have not been fully elucidated, partially due to the pathological complexity in animal TBI models. Although there are several in vitro TBI models, none of them closely mimic post-TBI microglial activation.
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