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ABSTRACT Introduction Amyloid precursor protein (APP) plays a central role in the pathophysiology of Alzheimer’s disease (AD), the leading cause of dementia worldwide. The accumulation of beta-amyloid protein is believed to be a crucial step in the development of AD. Therefore, understanding the complex biology of APP and its various cleavage products may be useful for developing effective therapeutic strategies for AD.
He founded Blauer Tactical Systems (BTS) in 1985 and it has grown into one of the world's leading consulting companies specializing in the research and development of performance psychology, personal safety, and close quarter tactics & scenario-based training for law enforcement, military, and professional self-defense instructors.
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