AbstractBackground: The differential diagnosis of tuberculous and malignant pleural effusion (PE) is extremely difficult and continues to pose clinical challenges.Aim: To evaluate the utility of pleural fluid Interferon gamma (IFN- ?), Tumor necrosis factor-alpha (TNF-?), Adenosine deaminase (ADA) levels with T cells subsets in differential diagnosis of malignant (MPE) and tuberculous pleural effusions (TPE).Methods: Forty patients with pleural effusion (20 tuberculous and 20 malignant) were...