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Data collection and analysis A total of 290 articles were obtained via the online database search (figure 1: flow diagram). Following removal of duplicates, 158 articles remained. The second screening was conducted by ‘Rayyan-systematic review software’. Two further duplicate articles were removed, with 156 remaining for review. Two independent authors separately performed a blind screen on the 156 abstracts.
Discussion There was no evidence of an overall association between our primary CV measures in offspring and maternal adversity. There was limited evidence to suggest that subtypes of adversity or specific may be associated with CV measures in an age-specific manner as well as an association between CV measures and some CpG probes.
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