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Main Article Content Keywords Skin and soft tissue infection, gene expression signature Abstract Background: Misdiagnosis of skin and soft tissue infections (SSTIs) due to clinical mimics can result in delay of care, unnecessary antibiotic exposure, and inappropriate hospitalization. Comprehensive screening of inflammatory genes in SSTIs could identify biomarkers to distinguish SSTIs from mimics.
In Reply Dr Kak highlights the challenge of treating cellulitis given the lack of culture data and the possibility of using surrogate biomarkers instead. In patients with group A streptococcal infections, although the antistreptolysin O response usually appears within 1 week and peaks 3 to 6 weeks after the infection, the decline in titers is less well characterized,1 and elevated titers can persist long after initial infection.
Importance Cellulitis is an infection of the deep dermis and subcutaneous tissue, presenting with expanding erythema, warmth, tenderness, and swelling. Cellulitis is a common global health burden, with more than 650 000 admissions per year in the United States alone. Observations In the United States, an estimated 14.5 million cases annually of cellulitis account for $3.7 billion in ambulatory care costs alone.
Op-Ed Contributor London AS we become increasingly dependent on the Internet, we need to be increasingly concerned about how it is regulated. The Federal Communications Commission has proposed "network neutrality" rules, which would prohibit Internet service providers from discriminating against or charging premiums for certain services or applications on the Web.
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