No abstract is available for this article. DATA AVAILABILITY STATEMENT Data sharing not applicable to this article as no datasets were generated or analysed during the current study. REFERENCES 1, , , , , , et al. The small molecule simufilam dose-dependently attenuates the worsening of seizures in a mouse model of tuberous sclerosis complex. Epilepsia. 2026; 67(7): 3753–3765. 2, . Comment on Wang et al. Simufilam reverses aberrant receptor interactions of filamin a in Alzheimer's disease. Int J Mol Sci.