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The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
1 Introduction Down syndrome (DS) is the most common chromosomal condition in the world [1, 2]. In the United States (US) specifically, DS occurs in 1 of every 700 live births in the US [3], accounting for approximately 206,000 people living with DS [4], though the exact and current prevalence is unknown because of lack of data and changing survival rates across decades.
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