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3. Discussion Since PAKs were first described around 30 years ago [108], considerable progress has been made in the understanding of these key signaling proteins [1,2,3,4,21,22]. However, a lot of questions still remain unanswered. In order to get a comprehensive insight into the functions and the integration of various cellular activities of a PAK, we screened for the binding partners of the budding yeast PAK Ste20 as an example.
Publication HistoryPublished online: September 06, 2017Accepted: August 30, 2017; Received in revised form: August 11, 2017; Received: February 26, 2017;
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