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Introduction Tumour microenvironment (TME) is crucial for cancer initiation, progression, and drug resistance. TME is formed by various fundamental constituents including stromal cells and immune cells (Cassetta et al., 2019; Li et al., 2023; Wang et al., 2023). Cancer development can be facilitated by tissue inflammation (Nost et al., 2021; Rajamaki et al., 2021).
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