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CHD congenital heart disease GWAS genome-wide association study NB neuroblastoma SNP single-nucleotide polymorphisms SNV single-nucleotide variants WGS whole-genome sequencing 1 Introduction Neuroblastoma (NB), an embryonal tumor of sympathetic nervous tissue, is the most frequent non-central nervous system solid tumor in children and accounts for 12%–15% of childhood cancer-related deaths [1-3].
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