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Articles by Alexandre E. Medina
E-cigarette aerosol-induced neurotoxicity during early brain development: mechanisms and outcomes
Electronic cigarettes (e-cigs) use has risen among youth, and sustained use during reproductive years increases the likelihood of consumption during gestation, bringing concerns as to neurodevelopmental consequences. Although often perceived as safer than combustible cigarettes, mounting evidence confirms neurotoxic effects of nicotine in e-cig aerosols, and indicates that components other than nicotine can be detrimental to the developing brain.
A Mathematical Sequence Representing Tonic Action Potential Spike Trains
Abstract This is a study outlining the regularity of action potential spikes. Through a stochastic study, we observed a series of strong correlations between the intervals of tonically firing spikes generated by injecting constant currents of varying intensities into layer V pyramidal neurons of the ferret medial prefrontal cortex. Based on this, we derived a formulaic relationship for the interspike intervals (ISIs).
A Mathematical Sequence Representing Tonic Action Potential Spike Trains
Abstract This is a study on the regularity of action potential spikes. Through a stochastic study, we found a series of strong correlations between the intervals of tonically firing spikes with the existence of spike frequency adaptation generated by injecting constant currents of varying intensities into layer 5 pyramidal neurons of the ferret medial prefrontal cortex. Based on this, we derived a relationship formula for the interspike intervals (ISIs).
Development of multisensory processing in ferret parietal cortex
RESEARCH REPORT Funding information: NINDS and NIAAA; grant numbers: NS064675 (MAM); AA13023 (AEM). Get access to the full version of this article. View access options below. Institutional Login Loading institution options... Log in to Wiley Online Library If you have previously obtained access with your personal account, please log in.
Programming, the century of neuronal diseases and mental health
Programming, software development. Many choose this path for being in high demand, therefore with a high salary, plus, you are your own boss. However, the programmers mental health awareness is not very much discussed as it should in a high media, as it can be a fatigue journey: a life-consuming, stressful, solitary, individualistic and competitive occupation.
Phosphorylation of CREB at Serine 142 and 143 Is Essential for Visual Cortex Plasticity
Research ArticleResearch Article: New Research, Sensory and Motor Systems Nisha S. Pulimood, Minerva Contreras, Molly E. Pruitt, Agnieszka Tarasiewicz and Alexandre E. Medina eNeuro 4 October 2021, 8 (5) ENEURO.0217-21.2021; DOI: https://doi.org/10.1523/ENEURO.0217-21.2021 Abstract The transcription factor cAMP response element-binding protein (CREB) is involved in a myriad of cellular functions in the central nervous system.
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