BRIEF RESEARCH REPORT article Volume 17 - 2026 | doi: 10.3389/fimmu.2026.1774160 Reviewed by BRIEF RESEARCH REPORT article NS Nicola Sariye Pollmann 1 1. Universitatsklinikum Jena, Jena, Germany 2. Ruhr-Universitat Bochum, Bochum, Germany Article metrics View details Abstract Thrombotic microangiopathies (TMAs) encompass a spectrum of severe pathological conditions mostly characterized by hemolytic anemia, microvascular thrombosis with organ failure, and thrombocytopenia.