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Articles by Ali Fan
Development and Validation of an UPLC-QqQ MS/MS Method for the Determination of Daraxonrasib, a New pan-KRAS Inhibitor, in Dog Plasma and Whole Blood and Its Application to Pharmacokinetic Studies
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Datasets supporting the results reported here may be obtained by contacting the corresponding author, provided the request is reasonable. References , , , , and . 2023.
Comprehensive Metabolic Profiling of Resigratinib, a Novel FGFR Inhibitor, Using Integrated LC-MS/MS and LC‐Orbitrap‐HRMS
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description rcm10141-sup-0001-Suppl-file.docxWord 2007 document , 297.6 KB Figure S1: LC-HRMS chromatograms of resigratinib and its metabolites following 60-min incubation with recombinant P450s. References 1, , , et al., “FGF/FGFR Signaling in Health and Disease,” Signal Transduction and Targeted Therapy 5, no. 1 (2020): 181, https://doi.org/10.1038/s41392-020-00222-7.
Evidence for cytochrome P450 3A4‐mediated metabolic activation of SCO‐267
CONFLICT OF INTEREST STATEMENT The authors reported no conflict of interest. REFERENCES , , , , & (1994). Dose of midazolam should be reduced during diltiazem and verapamil treatments. British Journal of Clinical Pharmacology, 37(3), 221–225. https://doi.org/10.1111/j.1365-2125.1994.tb04266.x , , , , , , & (2008). Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug.
Simultaneous determination of sinomenine and its metabolites desmethyl‐sinomenine and sinomenine N‐oxide in rat plasma by liquid chromatography tandem mass spectrometry
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description jssc8194-sup-0001-SuppMat.docx25.1 KB Supporting Information REFERENCES 1, . Research progress on pharmacological effects of sinomenine. Res Pract Chin Med. 2016; 30: 81–86. 2, , , , , , et al. Activation of PI3K/Akt and ERK signaling pathways antagonized sinomenine-induced lung cancer cell apoptosis. Mol Med Rep. 2012; 5: 1256–1260. 3, , , , .
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