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Dear Editor, We thank Drs Akhtar and Roman for their interest in our article, “Population Pharmacokinetic Modeling for the Iminosugar Lucerastat Supports Dose Adaptation in Patients with Fabry Disease and Moderate to Severe Renal Function Impairment.”1 Their letter raises three main points: external validation, exposure–response analyses, and heterogeneity between studies.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.