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Introduction Heart failure is a complex syndrome and considered the leading cause of hospitalization in patients over the age of 60 years, which accounts for about 30–40% of the mortality of these patients (Ponikowski et al., 2016). According to cardiac function, heart failure (HF) patients are currently classified as follows: (i) with preserved ejection fraction, (ii) with mid-range ejection fraction; and (iii) with reduced ejection fraction (HFrEF).
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