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1 INTRODUCTION Since its introduction in the 1970s, glyphosate has become a cornerstone of modern agriculture,1 enabling widespread adoption of herbicide-tolerant crops and conservation tillage practices. It remains the most widely used herbicide globally. Glyphosate functions by inhibiting the chloroplastic, nuclear-encoded enzyme 5-enolypyruvylshikimate-3-phosphate synthase (EPSPS),2 disrupting the synthesis of aromatic amino acids.
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